SPATA5 antibody (C-Term)

Catalog No. ABIN8112632

The Rabbit Polyclonal anti-SPATA5 antibody is suitable to detect SPATA5 in samples from Human. It has been validated for WB.

Quick Overview for SPATA5 antibody (C-Term) (ABIN8112632)

Target: SPATA5 (Spermatogenesis Associated 5 (SPATA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPATA5 Antibody

Binding Specificity: C-Term

Purpose: SPATA5 Antibody - C-terminal region

Sequence: LPLKQPELFK SYGIPAPRGV LLYGPPGTGK TMIARAVANE VGAYVSVING

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SPATA5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52814-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPATA5

Target: SPATA5 (Spermatogenesis Associated 5 (SPATA5))

Alternative Name: SPATA5

Background:

Background Information: This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants.

Gene Name: spermatogenesis associated 5

Alternative Symbols: AFG2, SPAF, EHLMRS

Protein Name: Spermatogenesis-associated protein 5

Molecular Weight: 76 kDa

Gene ID: 166378

NCBI Accession: NP_660208

UniProt: Q8NB90