SUV420H2/KMT5C antibody (N-Term)

Catalog No. ABIN8113128

The Rabbit Polyclonal anti-SUV420H2/KMT5C antibody (ABIN8113128) specifically detects SUV420H2/KMT5C in WB. The antibody is reactive with Mouse, Human, Cow, Dog, Horse, Rat and Guinea Pig samples.

Quick Overview for SUV420H2/KMT5C antibody (N-Term) (ABIN8113128)

Target: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Reactivity: Mouse, Human, Cow, Dog, Horse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUV420H2/KMT5C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SUV420H2/KMT5C Antibody

Binding Specificity: N-Term

Purpose: KMT5C Antibody - N-terminal region

Sequence: TLGGWTARYF QSRGPRQEAA LKTHVYRYLR AFLPESGFTI LPCTRYSMET

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SV422

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51248-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUV420H2/KMT5C

Target: SUV420H2/KMT5C (SUV420H2) (Suppressor of Variegation 4-20 Homolog 2 (SUV420H2))

Alternative Name: KMT5C

Background:

Background Information: SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009]

Gene Name: lysine methyltransferase 5C

Alternative Symbols: SUV420H2, Suv4-20h2

Protein Name: histone-lysine N-methyltransferase KMT5C

Molecular Weight: 50kDa

Gene ID: 84787

UniProt: Q86Y97