TUBA3E antibody (Middle Region)

Catalog No. ABIN8114935

This Rabbit Polyclonal antibody specifically detects TUBA3E in WB. It exhibits reactivity toward Human, Guinea Pig, Rabbit, Rat and Zebrafish (Danio rerio).

Quick Overview for TUBA3E antibody (Middle Region) (ABIN8114935)

Target: TUBA3E (Tubulin, alpha 3e (TUBA3E))

Reactivity: Human, Guinea Pig, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA3E antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TUBA3E Antibody

Binding Specificity: Middle Region

Purpose: TUBA3E Antibody - middle region

Sequence: RLSVDYSKKS KLEFAIYPAP QVSTAVVEPY NSILTTHTTL EHSDCAFMVD

Predicted Reactivity: Guinea Pig: 100%, Human: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TBA3E

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53516-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TUBA3E

Target: TUBA3E (Tubulin, alpha 3e (TUBA3E))

Alternative Name: TUBA3E

Background:

Background Information: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. This gene encodes an alpha tubulin that highly conserved among species. A missense mutation in this gene has been potentially linked to microlissencephaly and global developmental delay.

Gene Name: tubulin alpha 3e

Protein Name: tubulin alpha-3E chain

Molecular Weight: 49kDa

Gene ID: 112714

NCBI Accession: NP_997195

UniProt: Q6PEY2

Pathways: Microtubule Dynamics