ZNF346 antibody (C-Term)

Catalog No. ABIN8116516

This Rabbit Polyclonal antibody specifically detects ZNF346 in WB. It exhibits reactivity toward Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for ZNF346 antibody (C-Term) (ABIN8116516)

Target: ZNF346 (Zinc Finger Protein 346 (ZNF346))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF346 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF346 Antibody

Binding Specificity: C-Term

Purpose: ZNF346 Antibody - C-terminal region

Sequence: TKVEALHQNR EMIDPDKFCS LCHATFNDPV MAQQHYVGKK HRKQETKLKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 100%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ZN346

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62606-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF346

Target: ZNF346 (Zinc Finger Protein 346 (ZNF346))

Alternative Name: ZNF346

Background:

Background Information: The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: zinc finger protein 346

Alternative Symbols: JAZ, Zfp346

Protein Name: zinc finger protein 346

Molecular Weight: 32kDa

Gene ID: 23567

UniProt: Q9UL40