EXTL2 antibody (AA 5-110)

Catalog No. ABIN761051

Product Details anti-EXTL2 Antibody

Target: EXTL2 (Exostoses (Multiple)-Like 2 (EXTL2))

Binding Specificity: AA 5-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXTL

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EXTL2

Target: EXTL2 (Exostoses (Multiple)-Like 2 (EXTL2))

Alternative Name: Extl2 (EXTL2 Products)

Synonyms: 3000001D04Rik antibody, AW146439 antibody, EXTR2 antibody, exostoses (multiple)-like 2 antibody, exostosin like glycosyltransferase 2 antibody, exostosin-like glycosyltransferase 2 antibody, Extl2 antibody, EXTL2 antibody

Background:

EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and is responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Subcellular location: Cytoplasm, Secreted, Cell membrane

Synonyms: Alpha 1 4 N acetylhexosaminyltransferase EXTL2, Alpha GalNAcT EXTL2, Exostoses multiple like 2, Exostoses multiple like 2, Exostosin like 2, EXT L2, EXT related protein 2, EXTL 2, EXTR 2, EXTR2, Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase, Multiple exostoses like 2, Processed exostosin like 2, EXTL2_HUMAN.

Gene ID: 2134