OASL antibody (AA 1-50)

Catalog No. ABIN8119451

This Rabbit Polyclonal antibody specifically detects OASL in WB and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for OASL antibody (AA 1-50) (ABIN8119451)

Target: OASL (2'-5' Oligoadenylate Synthetase-Like (OASL))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OASL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OASL Antibody

Binding Specificity: AA 1-50

Purpose: OASL Antibody

Specificity: OASL Polyclonal Antibody detects endogenous levels of OASL

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human OASL. at AA range: 1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OASL

Target: OASL (2'-5' Oligoadenylate Synthetase-Like (OASL))

Alternative Name: OASL

Background:

Synonyms: 2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)

Background: caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.,

Gene Name: OASL

Protein Name: OASL

Gene ID: 8638

UniProt: Q15646