ACER2 antibody (AA 50-130)

Catalog No. ABIN8119661

This Rabbit Polyclonal antibody specifically detects ACER2 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for ACER2 antibody (AA 50-130) (ABIN8119661)

Target: ACER2 (Alkaline Ceramidase 2 (ACER2))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ACER2 Antibody

Binding Specificity: AA 50-130

Purpose: ASAH3L Antibody

Specificity: ASAH3L Polyclonal Antibody detects endogenous levels of ASAH3L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from ASAH3L . at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ACER2

Target: ACER2 (Alkaline Ceramidase 2 (ACER2))

Alternative Name: ASAH3L

Background:

Synonyms: ACER2, ASAH3L, PP11646, Alkaline ceramidase 2, AlkCDase 2, Alkaline CDase 2, haCER2, Acylsphingosine deacylase 3-like, N-acylsphingosine amidohydrolase 3-like

Background: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010],

Gene Name: ACER2

Protein Name: Alkaline ceramidase 2

Gene ID: 340485

UniProt: Q5QJU3

Pathways: Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process