Fetuin A antibody

Catalog No. ABIN8119683

The Rabbit Polyclonal anti-Fetuin A antibody is suitable to detect Fetuin A in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Fetuin A antibody (ABIN8119683)

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fetuin A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Fetuin A Antibody

Purpose: Fetuin-A Antibody

Specificity: This antibody detects endogenous levels of Human Fetuin-A

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Fetuin-A

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Fetuin A

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Alternative Name: Fetuin-A

Background:

Synonyms: Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A, Alpha-2-HS-glycoprotein chain B]

Background: function:Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.,polymorphism:There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256, AHSG*2 has Met-248/Ser-256.,similarity:Belongs to the fetuin family.,similarity:Contains 2 cystatin domains.,subunit:Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond.,tissue specificity:Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.,

Gene Name: AHSG FETUA PRO2743

Protein Name: Fetuin-A

Gene ID: 197

UniProt: P02765