alpha 2 Macroglobulin antibody (AA 1100-1180)

Catalog No. ABIN8119685

This Rabbit Polyclonal antibody specifically detects alpha 2 Macroglobulin in IHC, ELISA and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for alpha 2 Macroglobulin antibody (AA 1100-1180) (ABIN8119685)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Macroglobulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-alpha 2 Macroglobulin Antibody

Binding Specificity: AA 1100-1180

Purpose: Macroglobulin α-2 Antibody

Specificity: Macroglobulin α-2 Polyclonal Antibody detects endogenous levels of Macroglobulin α-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Macroglobulin alpha-2 . at AA range: 1100-1180

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Alternative Name: Macroglobulin alpha-2

Background:

Synonyms: A2M, CPAMD5, FWP007, Alpha-2-macroglobulin, Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5

Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008],

Gene Name: A2M

Protein Name: Alpha-2-macroglobulin

Gene ID: 2

UniProt: P01023

Pathways: Lipid Metabolism