ARTN antibody (AA 101-150)

Catalog No. ABIN8119810

The Rabbit Polyclonal anti-ARTN antibody (ABIN8119810) specifically detects ARTN in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ARTN antibody (AA 101-150) (ABIN8119810)

Target: ARTN (Artemin (ARTN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARTN antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ARTN Antibody

Binding Specificity: AA 101-150

Purpose: Artn Antibody

Specificity: The antibody detects endogenous Artn

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 101-150

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ARTN

Target: ARTN (Artemin (ARTN))

Alternative Name: Artn

Background:

Synonyms: Artemin (Enovin, Neublastin)

Background: This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016],

Gene Name: ARTN EVN

Protein Name: Artemin (Enovin) (Neublastin)

Gene ID: 9048

UniProt: Q5T4W7