Ataxin 3 antibody (AA 200-280)

Catalog No. ABIN8119839

The Rabbit Polyclonal anti-Ataxin 3 antibody is suitable to detect Ataxin 3 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Ataxin 3 antibody (AA 200-280) (ABIN8119839)

Target: Ataxin 3 (ATXN3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Ataxin 3 Antibody

Binding Specificity: AA 200-280

Purpose: ATX3 Antibody

Specificity: ATX3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Ataxin 3

Target: Ataxin 3 (ATXN3)

Alternative Name: ATX3

Background:

Background: ataxin 3(ATXN3) Homo sapiens Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder.The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016],

Gene Name: ATXN3 ATX3 MJD MJD1 SCA3

Protein Name: Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)

Gene ID: 4287

UniProt: P54252