BTLA antibody (AA 101-150)

Catalog No. ABIN8119932

The Rabbit Polyclonal anti-BTLA antibody is suitable to detect BTLA in samples from Human, Mouse and Rat. It has been validated for WB, FACS, ELISA, IHC and IF.

Quick Overview for BTLA antibody (AA 101-150) (ABIN8119932)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTLA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BTLA Antibody

Binding Specificity: AA 101-150

Purpose: CD272 Antibody

Specificity: CD272 Polyclonal Antibody detects endogenous levels of CD272 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: CD272

Background:

Synonyms: BTLA, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, CD antigen CD272

Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],

Gene Name: BTLA

Protein Name: B- and T-lymphocyte attenuator

Gene ID: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints