BBS2 antibody (AA 149-199)

Catalog No. ABIN8119956

The Rabbit Polyclonal anti-BBS2 antibody is suitable to detect BBS2 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for BBS2 antibody (AA 149-199) (ABIN8119956)

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BBS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BBS2 Antibody

Binding Specificity: AA 149-199

Purpose: BBS2 Antibody

Specificity: This antibody detects endogenous levels of BBS2 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BBS2 AA range: 149-199

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BBS2

Target: BBS2 (Bardet-Biedl Syndrome 2 (BBS2))

Alternative Name: BBS2

Background:

Background: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport.The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.[provided by RefSeq, Oct 2014],

Gene Name: BBS2

Protein Name: BBS2

Gene ID: 583

UniProt: Q9BXC9

Pathways: Hedgehog Signaling