BCLAF1 antibody (pSer531)

Catalog No. ABIN8119967

This Rabbit Polyclonal antibody specifically detects BCLAF1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BCLAF1 antibody (pSer531) (ABIN8119967)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCLAF1 Antibody

Binding Specificity: pSer531

Purpose: BCLAF1 (Phospho Ser531) Antibody

Specificity: This antibody detects endogenous levels of BCLAF1 (Phospho-Ser531) at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human BCLAF1 (Phospho-Ser531)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1

Background:

Synonyms: Bcl-2-associated transcription factor 1 (Btf)

Background: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: BCLAF1 BTF KIAA0164

Protein Name: BCLAF1 (Phospho-Ser531)

Gene ID: 9774

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus