BACE1 antibody (acLys316)

Catalog No. ABIN8119989

The Rabbit Polyclonal anti-BACE1 antibody is suitable to detect BACE1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for BACE1 antibody (acLys316) (ABIN8119989)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BACE1 Antibody

Binding Specificity: acLys316

Purpose: BACE (Acetyl Lys316) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat BACE (Acetyl Lys316)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human BACE (Acetyl Lys316)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE

Background:

Synonyms: Beta-secretase 1 (EC 3.4.23.46; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2)

Background: beta-secretase 1(BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015],

Gene Name: BACE1 BACE KIAA1149

Protein Name: BACE (Acetyl Lys316)

Gene ID: 23621

UniProt: P56817