BNP antibody (AA 89-139)

Catalog No. ABIN8120020

The Rabbit Polyclonal anti-BNP antibody (ABIN8120020) specifically detects BNP in IHC. The antibody is reactive with Human samples.

Quick Overview for BNP antibody (AA 89-139) (ABIN8120020)

Target: BNP (Brain Natriuretic Peptide (BNP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BNP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BNP Antibody

Binding Specificity: AA 89-139

Purpose: BNP Antibody

Specificity: This antibody detects endogenous levels of BNP at Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BNP AA range: 89-139

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Alternative Name: BNP

Background:

Synonyms: Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)

Background: Natriuretic peptide B(NPPB) Homo sapiensThis gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.

Gene Name: MLST8 GBL LST8

Protein Name: BNP

Gene ID: 64223

UniProt: Q9BVC4

Pathways: Hormone Activity