Bystin antibody (AA 127-177)

Catalog No. ABIN8120058

The Rabbit Polyclonal anti-Bystin antibody is suitable to detect Bystin in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Bystin antibody (AA 127-177) (ABIN8120058)

Target: Bystin (BYST)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bystin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Bystin Antibody

Binding Specificity: AA 127-177

Purpose: BYST Antibody

Specificity: This antibody detects endogenous levels of BYST at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BYST AA range: 127-177

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Bystin

Target: Bystin (BYST)

Alternative Name: BYST

Background:

Background: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi. [provided by RefSeq, Jul 2008],

Gene Name: BYSL

Protein Name: BYST

Gene ID: 705

UniProt: Q13895