Cathepsin H antibody (AA 220-300)

Catalog No. ABIN8120278

The Rabbit Polyclonal anti-Cathepsin H antibody (ABIN8120278) specifically detects Cathepsin H in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Cathepsin H antibody (AA 220-300) (ABIN8120278)

Target: Cathepsin H (CTSH)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Cathepsin H Antibody

Binding Specificity: AA 220-300

Purpose: Cathepsin H Antibody

Specificity: Cathepsin H Polyclonal Antibody detects endogenous levels of Cathepsin H protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Cathepsin H . at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cathepsin H

Target: Cathepsin H (CTSH)

Alternative Name: Cathepsin H

Background:

Synonyms: CTSH, CPSB, Pro-cathepsin H

Background: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],

Gene Name: CTSH

Protein Name: Pro-cathepsin H

Gene ID: 1512

UniProt: P09668

Pathways: Positive Regulation of Endopeptidase Activity