CD180 antibody (AA 221-270)

Catalog No. ABIN8120316

The Rabbit Polyclonal anti-CD180 antibody is suitable to detect CD180 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CD180 antibody (AA 221-270) (ABIN8120316)

Target: CD180 (CD180 Molecule (CD180))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD180 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD180 Antibody

Binding Specificity: AA 221-270

Purpose: CD180 Antibody

Specificity: CD180 Polyclonal Antibody detects endogenous levels of CD180 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from CD180 antigen at AA range: 221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD180

Target: CD180 (CD180 Molecule (CD180))

Alternative Name: CD180

Background:

Synonyms: CD180, LY64, RP105, CD180 antigen, Lymphocyte antigen 64, Radioprotective 105 kDa protein, CD180

Background: CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq, Jul 2008],

Gene Name: CD180

Protein Name: CD180 antigen

Gene ID: 4064

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades