CXCL2 antibody (AA 58-107)

Catalog No. ABIN8120505

The Rabbit Polyclonal anti-CXCL2 antibody is suitable to detect CXCL2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for CXCL2 antibody (AA 58-107) (ABIN8120505)

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CXCL2 Antibody

Binding Specificity: AA 58-107

Purpose: CXCL2 Antibody

Specificity: This antibody detects endogenous levels of Human GROβ

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GRObeta AA range: 58-107

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CXCL2

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Alternative Name: CXCL2

Background:

Synonyms: C-X-C motif chemokine 2 (Growth-regulated protein beta, Gro-beta, Macrophage inflammatory protein 2-alpha, MIP2-alpha) [Cleaved into: GRO-beta(5-73, GRO-beta-T, Hematopoietic synergistic factor, HSF, SB-251353)]

Background: function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,

Gene Name: CXCL2 GRO2 GROB MIP2A SCYB2

Protein Name: GROβ

Gene ID: 2920

UniProt: P19875

Pathways: Cellular Response to Molecule of Bacterial Origin