CXCR2 antibody (AA 1-50)

Catalog No. ABIN8120508

The Rabbit Polyclonal anti-CXCR2 antibody is suitable to detect CXCR2 in samples from Human. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for CXCR2 antibody (AA 1-50) (ABIN8120508)

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CXCR2 Antibody

Binding Specificity: AA 1-50

Purpose: IL-8RA Antibody

Specificity: The antibody detects endogenous IL-8RA

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Alternative Name: IL-8RA

Background:

Synonyms: C-X-C chemokine receptor type 1 (CXC-R1, CXCR-1, CDw128a, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1, CD antigen CD181)

Background: C-X-C motif chemokine receptor 1(CXCR1) Homo sapiens The protein encoded byThis gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008],

Gene Name: CXCR1 CMKAR1 IL8RA

Protein Name: C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)

Gene ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process