CX3CR1 antibody (AA 120-200)

Catalog No. ABIN8120511

The Rabbit Polyclonal anti-CX3CR1 antibody is suitable to detect CX3CR1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for CX3CR1 antibody (AA 120-200) (ABIN8120511)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CX3CR1 Antibody

Binding Specificity: AA 120-200

Purpose: Fractalkine Receptor Antibody

Specificity: Fractalkine Receptor Polyclonal Antibody detects endogenous levels of Fractalkine Receptor protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Fractalkine Receptor . at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: Fractalkine Receptor

Background:

Synonyms: CX3CR1, CMKBRL1, GPR13, CX3C chemokine receptor 1, C-X3-C CKR-1, CX3CR1, Beta chemokine receptor-like 1, CMK-BRL-1, CMK-BRL1, Fractalkine receptor, G-protein coupled receptor 13, V28

Background: Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes.The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

Gene Name: CX3CR1

Protein Name: CX3C chemokine receptor 1

Gene ID: 1524

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin