CHRNG antibody (AA 30-110)

Catalog No. ABIN8120530

The Rabbit Polyclonal anti-CHRNG antibody (ABIN8120530) specifically detects CHRNG in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CHRNG antibody (AA 30-110) (ABIN8120530)

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNG antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHRNG Antibody

Binding Specificity: AA 30-110

Purpose: ACHG Antibody

Specificity: ACHG Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHRNG

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Alternative Name: ACHG

Background:

Background: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009],

Gene Name: CHRNG ACHRG

Protein Name: Acetylcholine receptor subunit gamma

Gene ID: 1146

UniProt: P07510