CHD9 antibody

Catalog No. ABIN8120548

The Rabbit Polyclonal anti-CHD9 antibody (ABIN8120548) specifically detects CHD9 in IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for CHD9 antibody (ABIN8120548)

Target: CHD9 (Chromodomain Helicase DNA Binding Protein 9 (CHD9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD9 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CHD9 Antibody

Purpose: CHD9 Antibody

Specificity: CHD9 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: IHC 1:50-300. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHD9

Target: CHD9 (Chromodomain Helicase DNA Binding Protein 9 (CHD9))

Alternative Name: CHD9

Background:

Background: function:Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis.,PTM:Phosphorylated on serine and tyrosine residues.,sequence caution:Wrong choice of frame.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,subunit:Interacts with PPARA. Probably interacts with ESR1 and NR1I3.,tissue specificity:Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.,

Gene Name: CHD9 KIAA0308 KISH2 PRIC320 AD-013 x0008

Protein Name: Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein)

Gene ID: 80205

UniProt: Q3L8U1

Pathways: Regulation of Lipid Metabolism by PPARalpha