C6orf150 antibody

Catalog No. ABIN8120573

This Rabbit Monoclonal antibody specifically detects C6orf150 in WB, IHC, ELISA, IP and IF. It exhibits reactivity toward Human.

Quick Overview for C6orf150 antibody (ABIN8120573)

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This C6orf150 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AB1873

Product Details anti-C6orf150 Antibody

Purpose: cGAS Rabbit mAb

Specificity: This antibody detects endogenous levels of cGAS protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:100-1:500 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for C6orf150

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Alternative Name: cGAS

Background:

Synonyms: Protein MB21D1 (Mab-21 domain-containing protein 1)

Background: Enables several functions, including 2', 3'-cyclic GMP-AMP synthase activity, molecular condensate scaffold activity, and phosphatidylinositol-4, 5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont, intracellular signal transduction, and regulation of defense response. Located in nuclear body, plasma membrane, and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]

Gene Name: MB21D1 cGAS C6orf150

Protein Name: cGAS

Gene ID: 115004

UniProt: Q8N884

Pathways: Activation of Innate immune Response