BAAT1 antibody

Catalog No. ABIN8120576

This Rabbit Monoclonal antibody specifically detects BAAT1 in WB, IF, IP, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for BAAT1 antibody (ABIN8120576)

Target: BAAT1 (C7orf27) (Chromosome 7 Open Reading Frame 27 (C7orf27))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BAAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AB2251

Product Details anti-BAAT1 Antibody

Purpose: BRAT1 Rabbit mAb

Specificity: This antibody detects endogenous levels of BRAT1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IF, 1:100-1:300 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | FC, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for BAAT1

Target: BAAT1 (C7orf27) (Chromosome 7 Open Reading Frame 27 (C7orf27))

Alternative Name: BRAT1

Background:

Synonyms: BRAT1, BAAT1, C7orf27, BRCA1-associated ATM activator 1 , BRCA1-associated protein required for ATM activation protein 1,

Background: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex) . The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]

Gene Name: BRAT1, BAAT1, C7orf27

Protein Name: BRAT1

Gene ID: 221927

UniProt: Q6PJG6