Claudin 3 antibody (AA 150-220)

Catalog No. ABIN8120603

This Mouse Monoclonal antibody specifically detects Claudin 3 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for Claudin 3 antibody (AA 150-220) (ABIN8120603)

Target: Claudin 3 (CLDN3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Claudin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1448

Product Details anti-Claudin 3 Antibody

Binding Specificity: AA 150-220

Purpose: Claudin 3 mouse mAb

Specificity: The antibody can specifically recognize human Claudin 3 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 220 of the human Claudin 3 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: Claudin 3

Background:

Synonyms: Clostridium perfringens enterotoxin receptor 2, Rat ventral prostate. 1 protein homolog

Background: Claudin 3 is a 22 kDa membrane protein, belonging to the tight junction protein family. It plays the role of tight junction through calcium independent cell adhesion activity. It is expressed in the junction between ductal epithelium and acinar epithelium. There was an increased expression in ovarian cancer, and decreased expression in breast cancer was associated with epithelial mesenchymal transition phenotype.

Gene Name: CLDN3

Protein Name: Claudin 3

Gene ID: 1365

UniProt: O15551

Pathways: Hepatitis C