Claudin 3 antibody (AA 150-220)

Catalog No. ABIN8120604

The Mouse Monoclonal anti-Claudin 3 antibody is suitable to detect Claudin 3 in samples from Human. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for Claudin 3 antibody (AA 150-220) (ABIN8120604)

Target: Claudin 3 (CLDN3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Claudin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: AB1534

Product Details anti-Claudin 3 Antibody

Binding Specificity: AA 150-220

Purpose: Claudin 3 mouse mAb

Specificity: This antibody detects endogenous levels of Claudin 3 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 220 of the human Claudin 3 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 3

Target: Claudin 3 (CLDN3)

Alternative Name: Claudin 3

Background:

Synonyms: Clostridium perfringens enterotoxin receptor 2, Rat ventral prostate. 1 protein homolog

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Gene Name: CLDN3

Protein Name: Claudin 3

Gene ID: 1365

UniProt: O15551

Pathways: Hepatitis C