Claudin 4 antibody (AA 150-209)

Catalog No. ABIN8120606

This Rabbit Monoclonal antibody specifically detects Claudin 4 in IHC. It exhibits reactivity toward Human.

Quick Overview for Claudin 4 antibody (AA 150-209) (ABIN8120606)

Target: Claudin 4 (CLDN4)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Claudin 4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1345

Product Details anti-Claudin 4 Antibody

Binding Specificity: AA 150-209

Purpose: Claudin 4 Rabbit mAb (Ready to Use)

Specificity: The antibody can recognize humanClaudin 4 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 209 of the human Claudin 4 protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: Claudin 4

Background:

Synonyms: Clostridium perfringens enterotoxin receptor, Williams-Beuren syndrome chromosomal region 8 protein

Background: Claudin 4, a protein with molecular weight of 22 kDa, is one of the major tight junction proteins that mediate cellular polarity and differentiation. The expression of claudin 4 is low in the normal tissues of the lung, kidney, breast, prostate, bladder and gastrointestinal tract. It has reported that the expression level of claudin 4 is significantly up- regulate in gastric cancer and breast tumors.

Gene Name: CLDN4

Protein Name: Claudin 4

Gene ID: 1364

UniProt: O14493

Pathways: Hepatitis C