Claudin 4 antibody (AA 150-209)

Catalog No. ABIN8120609

This Mouse Monoclonal antibody specifically detects Claudin 4 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for Claudin 4 antibody (AA 150-209) (ABIN8120609)

Target: Claudin 4 (CLDN4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Claudin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: AB1535

Product Details anti-Claudin 4 Antibody

Binding Specificity: AA 150-209

Purpose: Claudin 4 mouse mAb

Specificity: This antibody detects endogenous levels of Claudin 4 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 209 of the human Claudin 4 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: Claudin 4

Background:

Synonyms: Clostridium perfringens enterotoxin receptor, Williams-Beuren syndrome chromosomal region 8 protein

Background: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre-and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013],

Gene Name: CLDN4

Protein Name: Claudin 4

Gene ID: 1364

UniProt: O14493

Pathways: Hepatitis C