Coagulation Factor X antibody (Cleaved-Arg179, Light Chain)

Catalog No. ABIN8120642

This Rabbit Polyclonal antibody specifically detects Coagulation Factor X in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Coagulation Factor X antibody (Cleaved-Arg179, Light Chain) (ABIN8120642)

Target: Coagulation Factor X (F10)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coagulation Factor X antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Coagulation Factor X Antibody

Binding Specificity: Cleaved-Arg179, Light Chain

Purpose: FA10 (light chain, Cleaved-Arg179) Antibody

Specificity: This antibody detects endogenous levels of Human FA10 (light chain, Cleaved-Arg179, protein was cleaved amino acid sequence between )

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human FA10 (light chain, Cleaved-Arg179)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Coagulation Factor X

Target: Coagulation Factor X (F10)

Alternative Name: FA10

Background:

Synonyms: Coagulation factor X (EC 3.4.21.6, Stuart factor, Stuart-Prower factor) [Cleaved into: Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain]

Background: catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma, synthesized in the liver.,

Gene Name: F10

Protein Name: FA10 (light chain, Cleaved-Arg179)

Gene ID: 2159

UniProt: P00742