F13A1 antibody (AA 400-500)

Catalog No. ABIN8120646

The Mouse Monoclonal anti-F13A1 antibody is suitable to detect F13A1 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for F13A1 antibody (AA 400-500) (ABIN8120646)

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This F13A1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1324

Product Details anti-F13A1 Antibody

Binding Specificity: AA 400-500

Purpose: Factor XIIIa mouse mAb

Specificity: The antibody can specifically recognize human Factor XIIIa protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Factor XIIIa protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: Factor XIIIa

Background:

Synonyms: bA525O21. 1 (coagulation factor XIII, A1 polypeptide) , Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, Coagulation factor XIII A1 subunit, Coagulation factor XIII, A polypeptide, Coagulation factor XIIIa, F13A, F13A_HUMAN, F13a1, Factor XIIIA, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein glutamine gamma glutamyltransferase A chain, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, Transglutaminase, plasma, Transglutaminase. plasma

Background: Factor XIIIa is found in plasma β Globulin. It is expressed in monocytes, macrophages, megakaryocytes, dendritic reticular cells in reactive lymph nodes, dermal dendritic cells, fibroblast like stromal cells and Kupffer cells in liver. It can be used as a marker of dermal dendritic cells. The tumors showed positive expression in dermal fibroma, atypical xanthoma, malignant fibrous histiocytoma, fibrous histiocytoma, some sarcomas, granulosa cell tumor and neurofibroma.

Gene Name: F13A1

Protein Name: Factor XIIIa

Gene ID: 2162

UniProt: P00488