CRY1 antibody (AA 120-200)

Catalog No. ABIN8120756

This Rabbit Polyclonal antibody specifically detects CRY1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CRY1 antibody (AA 120-200) (ABIN8120756)

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CRY1 Antibody

Binding Specificity: AA 120-200

Purpose: CRY1 Antibody

Specificity: CRY1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CRY1

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Alternative Name: CRY1

Background:

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014],

Gene Name: CRY1 PHLL1

Protein Name: Cryptochrome-1

Gene ID: 1407

UniProt: Q16526

Pathways: Response to Water Deprivation, Proton Transport