CRY2 antibody (AA 181-231)

Catalog No. ABIN8120757

The Rabbit Polyclonal anti-CRY2 antibody is suitable to detect CRY2 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for CRY2 antibody (AA 181-231) (ABIN8120757)

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRY2 Antibody

Binding Specificity: AA 181-231

Purpose: CRY2 Antibody

Specificity: This antibody detects endogenous levels of CRY2 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CRY2 AA range: 181-231

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CRY2

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Alternative Name: CRY2

Background:

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014],

Gene Name: CRY2 KIAA0658

Protein Name: CRY2

Gene ID: 1408

UniProt: Q49AN0

Pathways: Response to Water Deprivation, Protein targeting to Nucleus