COX2 antibody (AA 40-120)

Catalog No. ABIN8120862

The Rabbit Polyclonal anti-COX2 antibody is suitable to detect COX2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for COX2 antibody (AA 40-120) (ABIN8120862)

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-COX2 Antibody

Binding Specificity: AA 40-120

Purpose: MTCO2 Antibody

Specificity: COX2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for COX2

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Alternative Name: MTCO2

Background:

Background: cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110], also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.,

Gene Name: MT-CO2 COII COXII MTCO2

Protein Name: Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)

Gene ID: 4513

UniProt: P00403

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation