CKAP5 antibody (AA 1446-1496)

Catalog No. ABIN8120895

The Rabbit Polyclonal anti-CKAP5 antibody is suitable to detect CKAP5 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for CKAP5 antibody (AA 1446-1496) (ABIN8120895)

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKAP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CKAP5 Antibody

Binding Specificity: AA 1446-1496

Purpose: CKAP5 Antibody

Specificity: This antibody detects endogenous levels of CKAP5 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CKAP5 AA range: 1446-1496

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CKAP5

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Alternative Name: CKAP5

Background:

Background: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

Gene Name: CKAP5 KIAA0097

Protein Name: CKAP5

Gene ID: 9793

UniProt: Q14008

Pathways: M Phase