Desmoplakin antibody (AA 1546-1596)

Catalog No. ABIN8120974

The Rabbit Polyclonal anti-Desmoplakin antibody (ABIN8120974) specifically detects Desmoplakin in IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for Desmoplakin antibody (AA 1546-1596) (ABIN8120974)

Target: Desmoplakin (DSP)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoplakin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Desmoplakin Antibody

Binding Specificity: AA 1546-1596

Purpose: DESP Antibody

Specificity: This antibody detects endogenous levels of DESP at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human DESP AA range: 1546-1596

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Desmoplakin

Target: Desmoplakin (DSP)

Alternative Name: DESP

Background:

Background: This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Gene Name: DSP

Protein Name: DESP

Gene ID: 1832

UniProt: P15924

Pathways: Cell-Cell Junction Organization