Desmoplakin antibody (pSer165)

Catalog No. ABIN8120975

This Rabbit Polyclonal antibody specifically detects Desmoplakin in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Desmoplakin antibody (pSer165) (ABIN8120975)

Target: Desmoplakin (DSP)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoplakin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Desmoplakin Antibody

Binding Specificity: pSer165

Purpose: Desmoplakin (Phospho Ser165/166) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse Rat Desmoplakin (phospho-Ser165 or 166)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Desmoplakin (Ser165 and 166)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Desmoplakin

Target: Desmoplakin (DSP)

Alternative Name: Desmoplakin

Background:

Synonyms: Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)

Background: This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Gene Name: DSP

Protein Name: Desmoplakin (Ser165/166)

Gene ID: 1832

UniProt: P15924

Pathways: Cell-Cell Junction Organization