Pnk1 antibody (pSer114, pThr118)
Quick Overview for Pnk1 antibody (pSer114, pThr118) (ABIN8121033)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer114, pThr118
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Purpose
- PNK1 (Phospho Ser114/Thr118) Antibody
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Specificity
- This antibody detects endogenous levels of Human PNK1 (phospho-Ser114 or Thr118)
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
- Synthesized phosho peptide around human PNK1 (Ser114 and Thr118)
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Isotype
- IgG
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anti-DNA Kinase/phosphatase Pnk1 (PNK1) (AA 100-150) antibody
PNK1 Reactivity: Human WB, IHC (fp) Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB 1:500-2000,IHC 1:50-300
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- Pnk1 (PNK1) (DNA Kinase/phosphatase Pnk1 (PNK1))
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Alternative Name
- PNK1
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Background
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Synonyms: Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)]
Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010],
Gene Name: PNKP
Protein Name: PNK1 (Ser114/Thr118)
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Gene ID
- 11284
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UniProt
- Q96T60
Target
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