DNAJC2 antibody (pSer47)

Catalog No. ABIN8121046

The Rabbit Polyclonal anti-DNAJC2 antibody (ABIN8121046) specifically detects DNAJC2 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DNAJC2 antibody (pSer47) (ABIN8121046)

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNAJC2 Antibody

Binding Specificity: pSer47

Purpose: DNAJC2/MPP11 (Phospho Ser47) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse Rat DNAJC2/MPP11 (phospho-Ser47)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DNAJC2

Target: DNAJC2 (DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))

Alternative Name: DNAJC2/MPP11

Background:

Synonyms: DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)

Background: This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],

Gene Name: DNAJC2 MPHOSPH11 MPP11 ZRF1

Protein Name: DNAJC2/MPP11 (Ser47)

Gene ID: 27000

UniProt: Q99543

Pathways: Chromatin Binding