DOK2 antibody (pTyr345)

Catalog No. ABIN8121049

The Rabbit Polyclonal anti-DOK2 antibody (ABIN8121049) specifically detects DOK2 in IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for DOK2 antibody (pTyr345) (ABIN8121049)

Target: DOK2

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-DOK2 Antibody

Binding Specificity: pTyr345

Purpose: Dok-2 (phospho Tyr345) Antibody

Specificity: Phospho-Dok-2 (Y345) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y345.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DOK2

Target: DOK2

Alternative Name: Dok-2

Background:

Synonyms: DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2)

Background: docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

Gene Name: DOK2

Protein Name: Docking protein 2

Gene ID: 9046

UniProt: O60496