SIAH1 antibody (AA 157-207)
Quick Overview for SIAH1 antibody (AA 157-207) (ABIN8121121)
Target
See all SIAH1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 157-207
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Purpose
- SIAH1 Antibody
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Specificity
- This antibody detects endogenous levels of SIAH1 at Human/Rat
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human SIAH1 AA range: 157-207
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Isotype
- IgG
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Application Notes
- WB 1:500-2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
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Alternative Name
- SIAH1
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Background
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Background: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],
Gene Name: SIAH1 HUMSIAH
Protein Name: SIAH1
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Gene ID
- 6477
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UniProt
- Q8IUQ4
Target
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