EDC4 antibody

Catalog No. ABIN8121189

The Rabbit Polyclonal anti-EDC4 antibody is suitable to detect EDC4 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for EDC4 antibody (ABIN8121189)

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDC4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-EDC4 Antibody

Purpose: EDC4 Antibody

Specificity: EDC4 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Alternative Name: EDC4

Background:

Background: function:In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the WD repeat EDC4 family.,similarity:Contains 4 WD repeats.,subunit:Part of a decapping complex consisting of DCP1A, DCP2, EDC3, EDC4 and probably DDX6. Part of a complex consisting of DCP1A, EDC3, EDC4 and DDX6. Part of a complex consisting of DCP1B, EDC3, EDC4 and DDX6. Interacts with DCP2.,

Gene Name: EDC4 HEDLS

Protein Name: Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)

Gene ID: 23644

UniProt: Q6P2E9