Sec8 antibody (AA 512-562)

Catalog No. ABIN8121330

The Rabbit Polyclonal anti-Sec8 antibody is suitable to detect Sec8 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Sec8 antibody (AA 512-562) (ABIN8121330)

Target: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sec8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sec8 Antibody

Binding Specificity: AA 512-562

Purpose: EXOC4 Antibody

Specificity: This antibody detects endogenous levels of EXOC4 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human EXOC4 AA range: 512-562

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Sec8

Target: Sec8 (EXOC4) (Exocyst Complex Component 4 (EXOC4))

Alternative Name: EXOC4

Background:

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: EXOC4 KIAA1699 SEC8 SEC8L1

Protein Name: EXOC4

Gene ID: 60412

UniProt: Q96A65

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis