XPO1 antibody

Catalog No. ABIN8121340

The Rabbit Polyclonal anti-XPO1 antibody (ABIN8121340) specifically detects XPO1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for XPO1 antibody (ABIN8121340)

Target: XPO1 (Exportin 1 (XPO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-XPO1 Antibody

Purpose: CRM1 Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat CRM1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CRM1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for XPO1

Target: XPO1 (Exportin 1 (XPO1))

Alternative Name: CRM1

Background:

Synonyms: Exportin-1 (Exp1, Chromosome region maintenance 1 protein homolog)

Background: This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015],

Gene Name: XPO1 CRM1

Protein Name: CRM1

Gene ID: 7514

UniProt: O14980

Pathways: M Phase