FCAR antibody

Catalog No. ABIN8121411

The Rabbit Monoclonal anti-FCAR antibody is suitable to detect FCAR in samples from Human. It has been validated for WB, FACS, IHC, IP, ICC and IF.

Quick Overview for FCAR antibody (ABIN8121411)

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FCAR antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AB2217

Product Details anti-FCAR Antibody

Purpose: CD89 Rabbit mAb

Specificity: This antibody detects endogenous levels of CD89 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:•100-1:300 | IF, 1:100-1:300 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | FC, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: CD89

Background:

Synonyms: FCAR, CD89, Immunoglobulin alpha Fc receptor , IgA Fc receptor, CD antigen CD89,

Background: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: FCAR, CD89

Protein Name: CD89

Gene ID: 2204

UniProt: P24071