FTH1 antibody (Heavy Chain)

Catalog No. ABIN8121421

The Rabbit Polyclonal anti-FTH1 antibody (ABIN8121421) specifically detects FTH1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FTH1 antibody (Heavy Chain) (ABIN8121421)

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FTH1 Antibody

Binding Specificity: Heavy Chain

Purpose: Ferritin heavy chain Antibody

Specificity: Ferritin heavy chain Polyclonal Antibody detects endogenous levels of Ferritin heavy chain protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Ferritin heavy chain. AA range 120-170

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin heavy chain

Background:

Synonyms: FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein

Background: This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: FTH1

Protein Name: Ferritin heavy chain

Gene ID: 2495

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis