PSMA antibody (AA 100-200)

Catalog No. ABIN8121483

The Rabbit Monoclonal anti-PSMA antibody is suitable to detect PSMA in samples from Human. It has been validated for IHC.

Quick Overview for PSMA antibody (AA 100-200) (ABIN8121483)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PSMA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1470

Product Details anti-PSMA Antibody

Binding Specificity: AA 100-200

Purpose: Prostate-Specific Membrane Antigen (PSMA) Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human PSMA protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Prostate Specific Membrane Antigen protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Alternative Name: Prostate-Specific Membrane Antigen

Background:

Synonyms: Cell growth inhibiting protein 27,Cell growth-inhibiting gene 27 protein,FGCP,Folate hydrolase (prostate-specific membrane antigen) 1,Folate hydrolase 1,Folate hydrolase,Folate hydrolase prostate specific membrane antigen 1,FOLH 1,FOLH,Folh1,FOLH1_HUMAN,Folylpoly gamma glutamate carboxypeptidase,Folylpoly-gamma-glutamate carboxypeptidase,GCP 2,GCP II,GCP2,GCPII,GIG27,Glutamate carboxylase II,Glutamate carboxypeptidase 2,Glutamate carboxypeptidase II,Membrane glutamate carboxypeptidase,mGCP,N acetylated alpha linked acidic dipeptidase 1,N-acetylated-alpha-linked acidic dipeptidase I,NAALAD 1,NAALAD1,NAALAdase,NAALADase I,Prostate specific membrane antigen,Prostate specific membrane antigen variant F,Prostate-specific membrane antigen,PSM,PSMA,Pteroylpoly gamma glutamate carboxypeptidase,Pteroylpoly-gamma-glutamate carboxypeptidase

Background: PSMA is a 110 kDa type II transmembrane protein. The gene is located in 11q and is expressed in normal and neoplastic prostate epithelium, as well as in breast, duodenum, colonic mucosa, kidney and tumors of its origin. The expression of PSMA increased after cell carcinogenesis, which was positively correlated with tumor grade and hormone resistance. Combined with PSA can improve the diagnosis of prostate cancer metastasis.

Gene Name: FOLH1

Protein Name: Prostate-Specific Membrane Antigen

Gene ID: 2346

UniProt: Q04609