FH antibody

Catalog No. ABIN8121541

The Rabbit Polyclonal anti-FH antibody (ABIN8121541) specifically detects FH in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FH antibody (ABIN8121541)

Target: FH (Fumarate Hydratase (FH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FH Antibody

Purpose: FH Antibody

Specificity: The antibody detects endogenous fumarase proteins.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of Fumarate hydratase, mitochondrial

Isotype: IgG

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for FH

Target: FH (Fumarate Hydratase (FH))

Alternative Name: FH

Background:

Synonyms: Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)

Background: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008],

Gene Name: FH

Protein Name: Fumarate hydratase, mitochondrial

Gene ID: 2271

UniProt: P07954