GABARAP antibody (AA 26-75)

Catalog No. ABIN8121571

The Rabbit Polyclonal anti-GABARAP antibody (ABIN8121571) specifically detects GABARAP in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GABARAP antibody (AA 26-75) (ABIN8121571)

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABARAP Antibody

Binding Specificity: AA 26-75

Purpose: GABARAP Antibody

Specificity: GABARAP Polyclonal Antibody detects endogenous levels of GABARAP

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of GABARAP AA range: 26-75

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Alternative Name: GABARAP

Background:

Synonyms: GABA(A) receptor-associated protein-like 2

Background: function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 LC3 family.,subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1.,tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.,

Gene Name: GABARAPL2 FLC3A GEF2

Protein Name: GABARAP

Gene ID: 11345

UniProt: P60520

Pathways: Autophagy